Combination therapy such as chemotherapy and radiotherapy is often chosen,
depending on cases, for head and neck cancer in view of preservation of
potency. However, on the other hand, it is necessary to note the onset
of therapeutic side effect . A case is a 35 years-old woman. During chemoradiotherapy
for mesopharyngeal carcinoma, she developed shock suddenly and presented
with multiple organ failure, requiring intensive treatment. In addition,
she developed reversible central nerve symptoms during the course. Involvement
of bacterial translocation(BT) was thought as a cause of shock, and, the
reversible central nerve symptoms were considered to be the pathological
condition which was called as reversible posterior leukoencephalopathy
syndrome (RPLS). On the basis of clinical features, and the process that
led to a diagnosis in this case, We discuss these conditions. |
